Dihydro-analog and congener of capsaicin (Prod. No. BML-EI125) in chili peppers (Capsicum). Like capsaicin it is irritant. Dihydrocapsaicin accounts for about 22% of the total capsaicinoids mixture and has about the same pungency as capsaicin. Antioxidant. Reduces oxidation of serum lipids. Mutagenic.
Product Details
| Alternative Name: | 8-Methyl-N-vanillylnonanamide |
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| Formula: | C18H29NO3 |
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| MW: | 307.4 |
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| Source: | Isolated from Capsicum fruit. |
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| CAS: | 19408-84-5 |
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| RTECS: | RA5998000 |
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| Purity: | ≥85% (HPLC) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in chloroform, DMSO or 100% ethanol; sparingly soluble in water. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | +4°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Determination of capsaicin and dihydrocapsaicin in capsicum fruits by liquid chromatography-electrospray/time-of-flight mass spectrometry: A. Garces-Claver, et al.; J. Agric. Food Chem.
54, 9303 (2006),
Abstract;
Effects of capsaicin, dihydrocapsaicin, and curcumin on copper-induced oxidation of human serum lipids: K.D. Ahuja, et al.; J. Agric. Food Chem.
54, 6436 (2006),
Abstract;
Oxidative DNA damage by capsaicin and dihydrocapsaicin in the presence of Cu(II): S. Singh, et al.; Cancer Lett.
169, 139 (2001),
Abstract;
Dihydrocapsaicin treatment depletes peptidergic nerve fibers of substance P and alters mast cell density in the respiratory tract of neonatal sheep: R. Ramirez-Romero, et al.; Regul. Pept.
91, 97 (2000),
Abstract;
The mutagenicity of capsaicin and dihydrocapsaicin in V79 cells: T. Lawson & P. Gannett; Cancer Lett.
48, 109 (1989),
Abstract;
General Literature References
Dihydrocapsaicin (DHC), a saturated structural analog of capsaicin,induces autophagy in human cancer cells in a catalase-regulated manner: S.H. Oh, et al.; Autophagy
4, 1009 (2008),
Abstract;
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