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Ingenol (high purity)

PKC inhibitor
 
ALX-350-031-M001 1 mg 56.00 USD
 
ALX-350-031-M005 5 mg 234.00 USD
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Extremely weak protein kinase C (PKC) activator. Starting material for synthesis of ingenol derivatives.

Product Specification

Formula:C20H28O5
 
MW:348.4
 
CAS:30220-46-3
 
Purity:≥98% (HPLC)
 
Appearance:White to off-white powder.
 
Solubility:Soluble in DMSO and 100% ethanol.
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
Handling:Protect from light.
 
ALX-350-031
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ALX-350-031

Product Literature References

Total synthesis of ingenol: I. Kuwajima & K. Tanino; Chem. Rev. 105, 4661 (2005), (Review), Abstract;
Preconditioning of isolated rabbit cardiomyocytes: effects of glycolytic blockade, phorbol esters, and ischaemia: S. Armstrong & C.E. Gonote; Cardiovasc. Res. 28, 1700 (1994), Abstract;
Specific binding to protein kinase C by ingenol and its induction of biological responses: C.M. Hasler, et al.; Cancer Res. 52, 202 (1992), Abstract;

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