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Esculin . hydrate

Antioxidant
 
ALX-350-021-G005 5 g 30.00 USD
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Antioxidant used as a skin protectant. Shows vitamin P activity. Protects cells against DNA damage. Reduces ROS levels. Inhibits carcinogenesis.

Product Specification

Alternative Name:6,7-Dihydroxycoumarin 6-glucoside
 
Formula:C15H16O9 . H2O
 
MW:340.3 . 18.0
 
CAS:531-75-9
 
MI:14: 3698
 
RTECS:DJ3085000
 
Purity:≥98% (HPLC)
 
Identity:Determined by 1H-NMR.
 
Appearance:White to off-white powder.
 
Solubility:Soluble in methanol (50mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
ALX-350-021
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ALX-350-021

Product Literature References

Anti-apoptotic effect of esculin on dopamine-induced cytotoxicity in the human neuroblastoma SH-SY5Y cell line: D.L. Zhao, et al.; Neuropharmacology 53, 724 (2007), Abstract;
Effects of esculin and esculetin on the survival of Escherichia coli O157 in human faecal slurries, continuous-flow simulations of the rumen and colon and in calves: S.H. Duncan, et al.; Br. J. Nutr. 91, 749 (2004), Abstract;
Inhibitory effect of esculin on oxidative DNA damage and carcinogenesis induced by N-nitrosobis(2-oxopropyl)amine in hamster pancreas: T. Kaneko, et al.; Biofactors 22, 83 (2004), Abstract;
Suppression of lipid hydroperoxide-induced oxidative damage to cellular DNA by esculetin: T. Kaneko, et al.; Biol. Pharm. Bull. 26, 840 (2003), Abstract;
HPLC Analysis of Esculin and Fraxin in Horse-Chestnut Bark (Aesculus hippocastanum L.): G. Stanic, et al.; Croatica Chemica Acta 72, 827 (1999), Full Text

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