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3-Deoxy-3-fluoro-D-myo-inositol 1,4,5-trisphosphate . hexasodium salt

 
ALX-307-021-C100 100 µg 30.00 USD
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Equipotent to Ins(1,4,5)P3 in releasing intracellular calcium. The 3-position is blocked by fluorine, hence it cannot be converted to Ins(1,3,4,5)P4 by the action of 3-kinases. It may therefore provide a useful tool for studying the complex biochemical pathways in which InsP3 and InsP4 are closely interactive.

Product Specification

Alternative Name:3-F-Deoxy-Ins(1,4,5)P3 . 6Na
 
Formula:C6H8FO14P3 . 6Na
 
MW:416.0 . 137.9
 
CAS:129365-68-0
 
Purity:≥99% (31P-NMR)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in water.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Hygroscopic.
 
ALX-307-021
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ALX-307-021

Product Literature References

Synthesis of the First Optically Pure, Fluorinated Inositol 1,4,5-Trisphosphate of myo-Inositol Stereochemistry and Its Effect on Ca2+  Release in Swiss 3T3 Cells: A.P. Kozikowski, et al.; JACS 112, 7403 (1990),

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