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Ganglioside GD1a . disodium salt (bovine brain)

PKC inhibitor
ALX-302-007-M001 1 mg 64.00 USD
ALX-302-007-M005 5 mg 264.00 USD
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Replaces Prod. #: ALX-302-008

Differentiation marker for cell growth. Protein kinase C (PKC) inhibitor. The major ganglioside of the nervous system.

Product Specification

Alternative Name:Disialoganglioside GD1a . 2Na (bovine brain), GD1a . 2Na (bovine brain)
Sequence:[II3(Neu5Ac),IV3(Neu5Ac)GgOse4Cer] [[α-Neu5Ac-(2→3)]-β-Gal-(1→3)-β-GalNAc-(1→4)-[α-Neu5Ac-(2→3)]-β-Gal-(1→4)-β-Glc-(1→1')-Cer]
Formula:C84H146N4O39 . 2Na
MW:1836.1 . 46.0 (calculated on sphingosine C18:1 and stearic acid)
Purity:≥98% (TLC)
Solubility:Soluble in chloroform/methanol/DI water, 2:1:0.1
Long Term Storage:-20°C
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Product Literature References

Ganglioside GD1a suppresses LPS-induced pro-inflammatory cytokines in RAW264.7 macrophages by reducing MAPKs and NF-κB signaling pathways through TLR4: Y. Wang, et al.; Int. Immunopharmacol. 28, 136 (2015), Application(s): Cell Culture, Abstract;
Chromatographic Separation of Human Brain Gangliosides: L. Svennerholm; J. Neurochem. 10, 613 (1963), Abstract;

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