Replaces Prod. #: ALX-302-006
The major ganglioside of the extra-nervous system. Inhibits growth of epidermal cells.
Product Details
Alternative Name: | GM3 . Na (bovine brain), Monosialoganglioside GM3 . Na (bovine brain) |
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Sequence: | [II3Neu5AcLacCer] [α-Neu5Ac-(2→3)]-β-Gal(1→4)-β-Glc-(1→1')-Cer] |
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Formula: | C59H107N2O21 . Na |
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MW: | 1180.5 . 23.0 (calculated on sphingosine C18:1 and stearic acid) |
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CAS: | 54827-14-4 |
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Purity: | ≥98% (TLC) |
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Appearance: | Lyophilized. |
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Solubility: | Soluble in chlorform/methanol (2:1). |
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Shipping: | Ambient Temperature |
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Long Term Storage: | -20°C |
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Handling: | Protect from moisture. |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Involvement of ganglioside GT1b in glutamate release from neuroblastoma cells: S. Watanabe, et al.; Neurosci. Lett.
517, 140 (2012),
Abstract;
Ganglioside-mediated modulation of cell growth. Specific effects of GM3 on tyrosine phosphorylation of the epidermal growth factor receptor: E.G. Bremer, et al.; J. Biol. Chem.
261, 2434 (1986),
Abstract;
Full Text
Gangliosides: H. Wiegandt; New Comprehensive Biochemistry: Glycolipids 10, 199 (1985), (Book chapter),