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Farnesyltransferase inhibitor

 
ALX-290-005-M001 1 mg 116.00 USD
 
ALX-290-005-M005 5 mg 319.00 USD
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Stable, membrane permeable inhibitor of farnesyltransferase. Has 30-fold higher selectivity for farnesyltransferase over geranylgeranyltransferase. Potential anticancer drug.

Product Specification

Alternative Name:B581
 
Sequence:N-[(2S)-((2R)-Amino-3-mercaptopropylamino)-3-methylbutyl]-Phe-Met-OH
 
Formula:C22H38N4O3S2
 
MW:470.7
 
CAS:149759-96-6
 
Purity:≥90% (HPLC)
 
Appearance:White to off-white powder.
 
Solubility:Soluble in water or DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Hygroscopic.
 
290-005
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290-005

Product Literature References

Peptidomimetic inhibitors of Ras farnesylation and function in whole cells: A.M. Garcia, et al.; J. Biol. Chem. 268, 18415 (1993), Abstract; Full Text

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For Research Use Only. Not for use in diagnostic procedures.
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