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Malonaldehyde bis(dimethyl acetal)

 
ALX-280-018-L005 5 ml 33.00 USD
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Precursor of malondialdehyde (MDA), a naturally occuring product of lipid peroxidation and prostaglandin biosynthesis, which is also formed by oxidation of polyunsaturated fatty acids in foods. Reacts with DNA to form adducts to deoxyguanosine and deoxyadenosine.

Product Specification

Alternative Name:Malondialdehyde Precursor, MDA Precursor, 1,1,3,3-Tetramethoxypropane
 
Formula:C7H16O4
 
MW:164.2
 
CAS:102-52-3
 
MI:13: 5709 (Malondialdehyde (MDA))
 
Purity:≥98% (GLC)
 
Identity:Identity determined by IR.
 
Appearance:Colorless liquid.
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
Handling:Keep away from heat, sources of ignition and incompatibles such as oxidizing agents.
 
Technical Info/Product Notes:Malondialdehyde (MDA) is very hygroscopic and can be stored only for a short time. For biological experiments we recommend to use aqueous solutions of MDA freshly prepared by acid hydrolysis (1% H2SO4 at room temperature) of malonaldehyde bis(dimethyl acetal) (Prod. No. ALX-280-018).
 
280-018
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280-018

Product Literature References

Chemistry and biology of DNA damage by malondialdehyde: L.J. Marnett, et al.; IRAC Sci. Publ. 150, 17 (1999), Abstract;
Lipid peroxidation-DNA damage by malondialdehyde: L.J. Marnett, et al.; Mutat. Res. 424, 83 (1999), Abstract;
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes: H. Esterbauer, et al.; Free Radic. Biol. Med. 11, 81 (1991), Abstract;
Malonaldehyde in aqueous solution and its role as a measure of lipid oxidation in foods: T. W. Kwon, et al.; J. Food Sci. 29, 294 (1964),

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