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CK-869

Inhibitor of actin polymerization
 
ALX-270-507-M002 2 mg 49.00 USD
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Cell permeable inhibitor of Bos taurus Arp2/3 complex (IC50=11μM).Inhibits actin polymerization (IC50=7μM), stimulated by ActA, a comet tail formation inducer from Listeria monocytogenes.

Product Specification

Alternative Name:2-(3-Bromophenyl)-3-(2,4-dimethoxyphenyl)-4-thiazolidinone
 
Formula:C17H16BrNO3S
 
MW:394.3
 
CAS:388592-44-7
 
Purity:≥95%
 
Appearance:White solid.
 
Solubility:Soluble in DMSO (>5mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
270-507
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270-507

Product Literature References

Characterization of two classes of small molecule inhibitors of Arp2/3 complex: B.J. Nolen, et al.; Nature 460, 1031 (2009), Abstract;

General Literature References

Arp2 links autophagic machinery with the actin cytoskeleton: I. Monastyrska, et al.; Mol. Biol. Cell 19, 1962 (2008), Abstract; Full Text

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