Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

UPF1035

PARP-2 inhibitor
 
ALX-270-498-M001 1 mg 55.00 USD
 
ALX-270-498-M005 5 mg 217.00 USD
Do you need bulk/larger quantities?
 
PARP-2 specific inhibitor with 60-fold selectivity for PARP-2 (IC50=0.15 ± 0.04μM) over PARP-1 (IC50=9.0 ± 0.7μM). Can be used for further characterization of PARP-2 in pathophysiological conditions.

Product Specification

Alternative Name:5-Benzoyloxy-3,4-dihydroisoquinolin-1(2H)-one
 
Formula:C16H11NO3
 
MW:265.3
 
CAS:370872-09-6
 
Purity:≥95% (HPLC)
 
Solubility:Soluble in DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Not stable in basic conditions.
 
270-498
Please mouse over
270-498

Product Literature References

Selective PARP-2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post-ischaemic brain damage: F. Moroni, et al.; Br. J. Pharmacol. 157, 854 (2009), Abstract;
On the way to selective PARP-2 inhibitors. Design, synthesis, and preliminary evaluation of a series of isoquinolinone derivatives: R. Pellicciari, et al.; ChemMedChem 3, 914 (2008), Abstract;

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
PARP
By biological activity:
PARP Inhibitor
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Related Literature

Product Flyers
The PARP Family & ADP Ribosylation
The PARP Family & ADP Ribosylation
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,