Trandolapril

ACE inhibitor



ALX-270-493-M010	10 mg	98.00 USD

ALX-270-493-M050	50 mg	392.00 USD

Angiotensin-converting enzyme (ACE) inhibitor with long biological half-life and a high degree of lipophilicity.

Product Specification

Alternative Name:	RU-44570

Formula:	C₂₄H₃₄N₂O₅

MW:	430.5

Purity:	≥98%

Appearance:	White to off-white crystalline powder.

CAS:	87679-37-6

MI:	14: 9568

RTECS:	NL6015178

Solubility:	Soluble in methanol, dichloromethane or DMSO.

Long Term Storage:	+20°C

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Product Literature References

Induction of apoptosis in leukemic cell lines treated with captopril, trandolapril and losartan: A new role in the treatment of leukaemia for these agents: S. De la Iglesia Inigo, et al.; Leuk. Res. 33, 810 (2009), Abstract;

Concomitant calcium entry blockade and inhibition of the renin-angiotensin system: a rational and effective means for treating hypertension: B. Gojanovic, et al.; J. Renin Angiotensin Aldosterone Syst. 9, 1 (2008), (Review), Abstract;

Angiotensin-converting enzyme inhibitors and coronary heart disease prevention: R. Donelly & G. Manning; J. Renin Angiotensin Aldosterone Syst. 8, 13 (2007), (Review), Abstract;

Vascular affinity of trandolapril: M. Miyazaki, et al.; Am. J. Hypertens. 8, 63S (1995), Abstract;

Trandolapril. How does it differ from other angiotensin converting enzyme inhibitors?: F. Zannad; Drugs 46 Suppl 2, 172 (1993), (Review), Abstract;

Angiotensin-converting enzyme inhibition, anti-hypertensive activity and hemodynamic profile of trandolapril (RU 44570): N.L. Brown, et al.; Eur. J. Pharmacol. 148, 79 (1988), Abstract;