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Ciprofibrate

PPARα activator
 
ALX-270-475-M025 25 mg 55.00 USD
 
ALX-270-475-M100 100 mg 163.00 USD
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Hypolipidemic compound. PPARα (peroxisome proliferator-activated receptor α) agonist.

Product Specification

Alternative Name:2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
 
Formula:C13H14Cl2O3
 
MW:289.2
 
CAS:52214-84-3
 
MI:14: 2313
 
RTECS:UF0880000
 
Purity:≥98% (HPLC)
 
Appearance:White to light yellow powder.
 
Solubility:Soluble in DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
270-475
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Product Literature References

P450 CYP2C epoxygenase and CYP4A ω-hydroxylase mediate ciprofibrate-induced PPARα-dependent peroxisomal proliferation: A. Gatica, et al.; J. Lipid Res. 48, 924 (2007), Abstract; Full Text
Differences in cell proliferation in rodent and human hepatic derived cell lines exposed to ciprofibrate: M.C. Clemencet, et al.; Cancer Lett. 222, 217 (2005), Abstract;
Comparison of the effects of various peroxisome proliferators on peroxisomal enzyme activities, DNA synthesis, and apoptosis in rat and human hepatocyte cultures: V. Goll, et al.; Toxicol. Appl. Pharmacol. 160, 21 (1999), Abstract;
Phosphorylation of peroxisome proliferator-activated receptor alpha in rat Fao cells and stimulation by ciprofibrate: P. Passilly, et al.; Biochem. Pharmacol. 58, 1001 (1999), Abstract;

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