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HSD Inhibitor 23

11-β-hydroxysteroid dehydrogenase inhibitor
 
ALX-270-474-M001 1 mg 195.00 USD
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Selective, potent and cell permeable small molecule inhibitor of 11-β-hydroxysteroid dehydrogenase.

Product Specification

Alternative Name:N-(5-Hydroxytricyclo[3.3.1.13,7]dec-2-yl)-α,α-dimethyl-4-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazineacetamide
 
Formula:C24H33F3N4O2
 
MW:466.5
 
CAS:868604-75-5
 
Purity:≥95%
 
Identity:Identity determined by MS, 1H- and 13C-NMR.
 
Appearance:White to off-white solid.
 
Solubility:Soluble in DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
270-474
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270-474

Product Literature References

Discovery and metabolic stabilization of potent and selective 2-amino-N-(adamant-2-yl) acetamide 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: J.J. Rohde, et al.; J. Med. Chem. 50, 149 (2007), Abstract; Full Text

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Dehydrogenase
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