Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

AR-A014418

GSK-3 inhibitor
 
ALX-270-468-M001 1 mg 66.00 USD
Do you need bulk/larger quantities?
 
Cell permeable, specific and potent inhibitor of glycogen synthase kinase-3 (GSK-3) (IC50=104nM). Inhibition is competitive with respect to ATP (Ki=38nM).

Product Specification

Alternative Name:N-(4-Methoxybenzyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea
 
Formula:C12H12N4O4S
 
MW:308.3
 
Source:Synthetic.
 
CAS:487021-52-3
 
Purity:≥95% (HPLC)
 
Identity:Identity determined by 1H-NMR.
 
Appearance:White to off-white solid.
 
Solubility:Soluble in DMSO, methanol, 100% ethanol or ethyl acetate.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
270-468
Please mouse over
270-468

Product Literature References

Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo: W. Noble, et al.; PNAS 102, 6990 (2005), Abstract; Full Text
AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test: T.D. Gould, et al.; Int. J. Neuropsychopharmacol. 7, 387 (2004), Abstract;
Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418: R. Bhat, et al.; J. Biol. Chem. 278, 45937 (2003), Abstract; Full Text

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
GSK
By biological activity:
GSK Inhibitor
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Related Literature

Brochures
Integrated solutions for screening Wnt regulators
Integrated solutions for screening Wnt regulators
Download as PDF

Catalogs
Diabetes Catalog
Diabetes Catalog
Download as PDF

Brochures
Essential Research Tools for Neurodegeneration & Neural Signaling
Essential Research Tools for Neurodegeneration & Neural Signaling
Download as PDF

Technical Posters
Disease-Associated Stress Signaling
Disease-Associated Stress Signaling
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,