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nor-NOHA . acetate

Arginase inhibitor
 
ALX-270-467-M001 1 mg 42.00 USD
 
ALX-270-467-M005 5 mg 109.00 USD
 
ALX-270-467-M025 25 mg 432.00 USD
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Potent and reversible arginase inhibitor. Specifically interacts with the manganese-cluster of the arginase active site. Does not act as a substrate or as an inhibitor of NOS.

Product Specification

Alternative Name:Nω-Hydroxy-nor-L-arginine . acetate
 
Formula:C5H12N4O3 . CH3COOH
 
MW:176.2 . 60.1
 
CAS:189302-40-7
 
Purity:≥97% (TLC)
 
Appearance:White to slightly yellowish powder.
 
Solubility:Soluble in water (50mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Very hygroscopic.
 
270-467
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270-467

Product Literature References

A natural compound macelignan protects midbrain dopaminergic neurons from inflammatory degeneration via microglial arginase-1 expression: K. Kiyofuji, et al.; Eur. J. Pharmacol. 760, 129 (2015), Application(s): Cell Culture, Abstract;
The new alpha-amino acid Nomega-hydroxy-nor-L-arginine: a high-affinity inhibitor of arginase well adapted to bind to its manganese cluster: J. Custot, et al.; JACS 119, 4086 (1997),

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