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United States 

PQ401

IGF-1 receptor inhibitor
 
ALX-270-459-M005 5 mg 112.00 USD
 
Potent inhibitor of insulin-like growth factor I receptor (IGF-IR) signalling and breast cancer cell growth in culture and in vivo.

Product Specification

Alternative Name:IGF-IR Inhibitor, N-(5-Chloro-2-methoxyphenyl)-N’-(2-methyl-4-quinolinyl)urea
 
Formula:C18H16ClN3O2
 
MW:341.8
 
CAS:196868-63-0
 
Purity:≥98% (HPLC (UV))
 
Appearance:Off-white solid.
 
Solubility:Soluble in DMSO (10mg/ml) or methanol (7mg/ml).
 
Long Term Storage:-20°C
 
270-459
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270-459

Product Literature References

Diarylureas are small-molecule inhibitors of insulin-like growth factor I receptor signaling and breast cancer cell growth: K.L. Gable, et al.; Mol. Cancer Ther. 5, 1079 (2006), Abstract;

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