2-Amino-4-methylpyridine

iNOS inhibitor



ALX-270-449-G001	1 g	13.00 USD

Potent inhibitor of inducible nitric oxide synthase (iNOS; NOS II) both in vitro and in vivo. Analgesic agent.

Product Specification

Alternative Name:	2-Amino-4-picoline

Formula:	C₆H₈N₂

MW:	108.1

Appearance:	White to off-white solid.

CAS:	695-34-1

MI:	14: 466

RTECS:	TJ5150000

Solubility:	Soluble in 100% ethanol, methanol, dimethylformamide or water.

Long Term Storage:	-20°C

Use/Stability:	Stable for 3 years after receipt when stored at -20°C.

Hazard:	TOXIC.

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Product Literature References

Inhibition of nitric oxide synthase aggravates cisplatin-induced nephrotoxicity: effect of 2-amino-4-methylpyridine: S.Y. Saad, et al.; Chemotherapy 48, 309 (2002), Abstract;

Analgesic activity of 2-amino-4-methylpyridine, a novel NO synthase inhibitor: E.R. Pettipher, et al.; Inflamm. Res. 46 Suppl 2, S135 (1997), Abstract;

2-Amino-4-methylpyridine as a potent inhibitor of inducible NO synthase activity in vitro and in vivo: W.S. Faraci, et al.; Br. J. Pharmacol. 119, 1101 (1996), Abstract;