Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

AMI-1

PRMT inhibitor
 
ALX-270-440-M005 5 mg 105.00 USD
 
ALX-270-440-M025 25 mg 432.00 USD
Do you need bulk/larger quantities?
 
Potent, cell permeable and specific inhibitor of protein arginine N-methyltransferases (PRMTs) (IC50=8.8µM for human PRMT1 and 3.0µM for yeast Hmt1p). Does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site. Exhibits only minimal effects on lysine N-methyltransferases. Suppresses the transcriptional coactivator activity of PRMT1 and PRMT4. Inhibitor of HIV-1 RT polymerase (IC50=5.0µM).

Product Specification

Formula:C21H12N2O9S2Na4
 
MW:592.4
 
CAS:20324-87-2
 
Purity:≥98% (HPLC)
 
Identity:Determined by NMR.
 
Appearance:Brown solid.
 
Solubility:Soluble in water, 100% ethanol or DMSO.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Handling:Protect from light. Hygroscopic. After reconstitution, prepare aliquots and store at -20°C.
 
270-440
Please mouse over
270-440

Product Literature References

Small molecule regulators of protein arginine methyltransferases: D. Cheng, et al.; J. Biol. Chem. 279, 23892 (2004), Abstract; Full Text
A novel mechanism for inhibition of HIV-1 reverse transcriptase: A.G. Skillman, et al.; Bioorg. Chem. 30, 443 (2002), Abstract;

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
PRMT
By biological activity:
PRMT Inhibitor
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Related Literature

Brochures
Epigenetics
Epigenetics
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,