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SANT-2

Smoothened inhibitor
 
ALX-270-436-M001 1 mg 198.00 USD
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Cell permeable antagonist of the Smoothened (Smo) protein function. Inhibitor of SAG (Prod. No. ALX-270-426) activity. Chemical tool to study the Hedgehog (Hh) signalling pathway and to explore therapeutic uses for inhibitors of Smo.

Product Specification

Alternative Name:N-[3-(1H-Benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide
 
Formula:C26H26ClN3O4
 
MW:480.0
 
CAS:329196-48-7
 
Purity:≥95%
 
Identity:Identity determined by MS, 1H- and 13C-NMR.
 
Appearance:White to off-white solid.
 
Solubility:Soluble in DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 6 months when stored at -20°C in the dark.
 
Handling:Protect from light.
 
270-436
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270-436

Product Literature References

Small molecule modulation of Smoothened activity: J.K. Chen, et al.; PNAS 99, 14071 (2002), Abstract; Full Text

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SAG 

Smoothened ligand
364590-63-6, ≥95% (HR-MS, 1H-NMR, 13C-NMR) | Print as PDF
 
ALX-270-426-M001 1 mg 235.00 USD
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