Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Gallotannin

Inhibitor of PARG and eNOS
 
ALX-270-418-G001 1 g 35.00 USD
Do you need bulk/larger quantities?
 
Inhibitor of poly(ADP-ribose) glycohydrolase (PARG). Cytoprotective in oxidatively stressed cells. Inhibitor of endothelial nitric oxide synthase (eNOS; NOS III) and weak inhibitor of inducible (iNOS; NOS II) and neuronal nitric oxide synthase (nNOS; NOS I). Induces cyclooxygenase-2 (COX-2) expression. Free radical scavenger.

Product Specification

Alternative Name:Tannic acid
 
Formula:C76H52O46
 
MW:1701.2
 
Source:Occurs in the bark and fruit of many plants, notably in the bark of the oak species, in sumac and myrobalan.
 
CAS:1401-55-4
 
MI:14: 9052
 
RTECS:WW5075000
 
Purity:≥95%
 
Appearance:Beige to light brown powder.
 
Solubility:Soluble in water, 100% ethanol, acetone or warm glycerol.
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
Handling:Protect from light.
 
270-418
Please mouse over
270-418

Product Literature References

Diadenosine 5′, 5′′′-P1,P4-tetraphosphate (Ap4A) is synthesized in response to DNA damage and inhibits the initiation of DNA replication: A.S. Marriott, et al.; DNA Repair (Amst.) 33, 90 (2015), Application(s): Cell Culture, Abstract;
The efficacy of protective effects of tannic acid, gallic acid, ellagic acid, and propyl gallate against hydrogen peroxide-induced oxidative stress and DNA damages in IMR-90 cells: C.H. Chen, et al.; Mol. Nutr. Food Res. 51, 962 (2007), Abstract;
Prominent free radicals scavenging activity of tannic acid in lead-induced oxidative stress in experimental mice: I.H. El-Sayed, et al.; Toxicol. Ind. Health 22, 157 (2006), Abstract;
Tannic acid in plant dust causes airway obstruction: D. Taubert, et al.; Thorax 60, 789 (2005), Abstract;
Inhibition of poly(ADP-ribose) glycohydrolase by gallotannin selectively up-regulates expression of proinflammatory genes: E. Rapizzi, et al.; Mol. Pharmacol. 66, 890 (2004), Abstract;
Green tea polyphenols and tannic acid act as potent inhibitors of phorbol ester-induced nitric oxide generation in rat hepatocytes independent of their antioxidant properties: R.C. Srivastava, et al.; Cancer Lett. 153, 1 (2000), Abstract;
The poly(ADP-ribose) glycohydrolase inhibitor gallotannin blocks oxidative astrocyte death: W. Ying, et al.; Neuroreport 11, 1385 (2000), Abstract;
Inhibition of constitutive endothelial NO-synthase activity by tannin and quercetin: M. Chiesi & R. Schwaller; Biochem. Pharmacol. 49, 495 (1995), Abstract;

Related Literature

Brochures
Comprehensive Tools for Quantifying Cellular Responses to Oxidative Damage
Comprehensive Tools for Quantifying Cellular Responses to Oxidative Damage
Download as PDF

Brochures
Stem Cells
Stem Cells
Download as PDF

Product Flyers
The PARP Family & ADP Ribosylation
The PARP Family & ADP Ribosylation
Download as PDF

Technical Posters
Disease-Associated Stress Signaling
Disease-Associated Stress Signaling
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,