Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

N-Oxalyl-D-alanine

FIH inhibitor
 
ALX-270-414-M050 50 mg 174.00 USD
Do you need bulk/larger quantities?
 
Cell permeable, potent competitive inhibitor of factor inhibiting HIF asparagine hydroxylase (FIH, IC50<0.4mM). Does not inhibit PHDs (prolyl hydroxylase domain-containing proteins; HIF-PHs).

Product Specification

Alternative Name:NODA, N-Oxalyl-2R-alanine, NOxRA
 
Formula:C5H7NO5 . H2O
 
MW:161.1 . 18.0
 
CAS:136868-52-5
 
Purity:≥98% (TLC)
 
Identity:Determined by NMR.
 
Appearance:White to off-white solid.
 
Solubility:Soluble in water or DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Very hygroscopic.
 
270-414
Please mouse over
270-414

Product Literature References

Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha: J.M. Elkins, et al.; J. Biol. Chem. 278, 1802 (2003), Abstract;
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation: P. Jaakkola, et al.; Science 292, 468 (2001), Abstract;

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
FIH
By biological activity:
FIH Inhibitor
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Related Literature

Brochures
Comprehensive Tools for Quantifying Cellular Responses to Oxidative Damage
Comprehensive Tools for Quantifying Cellular Responses to Oxidative Damage
Download as PDF

Technical Posters
Disease-Associated Stress Signaling
Disease-Associated Stress Signaling
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,