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3-Amino-1H-pyrazolo[3,4-b]quinoxaline

Inhibitor of CDK and GSK
 
ALX-270-387-M001 1 mg 47.00 USD
 
ALX-270-387-M005 5 mg 155.00 USD
 
Selective inhibitor of CDK1/cyclin B (IC50=600nM), CDK5/p25 (IC50=400nM) and GSK-3β (IC50=1µM). Does not inhibit Cdc25 phosphatase activity (IC50>10µM).

Product Specification

Formula:C9H7N5
 
MW:185.2
 
Purity:≥98% (HPLC)
 
Appearance:Red solid.
 
CAS:40254-90-8
 
Solubility:Soluble in DMSO.
 
Long Term Storage:+4°C
 
Handling:Packaged under inert gas.
Protect from light.
 
270-387
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270-387

Product Literature References

Pyrazolo[3,4-b]quinoxalines. A new class of cyclin-dependent kinases inhibitors: M.A. Ortega, et al.; Bioorg. Med. Chem. 10, 2177 (2002), Abstract;

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