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trans-HR22C16

Mitotic kinesin Eg5 inhibitor
 
ALX-270-373-M001 1 mg 114.00 USD
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Cell permeable non-tubulin-interacting mitosis inhibitor. Blocks mitosis (IC50=800nM) by binding to the mitotic kinesin Eg5.

Product Specification

Formula:C23H23N3O3
 
MW:389.5
 
CAS:462630-41-7
 
Purity:≥95%
 
Identity:Identity determined by MS, 1H- and 13C-NMR.
 
Appearance:Yellow to ocher solid.
 
Solubility:Soluble in DMSO (10mg/ml).
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
270-373
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270-373

Product Literature References

HR22C16: A Potent Small-Molecule Probe for the Dynamics of Cell Division: S. Hotha, et al.; Angew. Chem. Int. Ed. Engl. 42, 2379 (2003), Abstract;

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Kinesin
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Kinesin Inhibitor
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Cell Cycle - Mitosis, CDKS & Cell Cycle Signaling
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