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2-Thio(3-iodobenzyl)-5-(1-pyridyl)-[1,3,4]-oxadiazole

GSK-3β inhibitor
 
ALX-270-358-M005 5 mg 199.00 USD
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Potent inhibitor of glycogen synthase kinase-3β (GSK-3β) (IC50=390nM).

Product Specification

Alternative Name:TIBPO
 
Formula:C14H10IN3OS
 
MW:395.2
 
CAS:478482-75-6
 
Formulation:Lyophilized.
 
Purity:≥95% (HPLC)
 
Appearance:Yellow solid.
 
Solubility:Soluble in DMSO (10mg/ml) or 100% ethanol.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Handling:Protect from light and moisture. Keep under inert gas.
 
270-358
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270-358

Product Literature References

Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors: L. Naerum, et al.; Bioorg. Med. Chem. Lett. 12, 1525 (2002), Abstract;

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