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3-O-Methyl-N-acetyl-D-glucosamine

N-Acetylglucosamine kinase inhibitor
 
ALX-270-343-M005 5 mg 217.00 USD
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Inhibitor of N-acetylglucosamine kinase (Ki=17µM) and N-acetylmannosamine kinase (Ki=80µM). It has been found that 3-OMe-GlcNAc potently inhibits glucose phosphorylation by N-acetylglucosamine kinase whereas glucokinase is not at all affected by this hexosamine.

Product Specification

Alternative Name:3-OMe-GlcNAc
 
Formula:C9H17NO6
 
MW:235.2
 
CAS:94825-74-8
 
Purity:≥98% (1H-NMR)
 
Appearance:White to off-white powder.
 
Solubility:Soluble in DMSO (10mg/ml) or water (10mg/ml).
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
270-343
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270-343

Product Literature References

Utility of 3-O-methyl-N-acetyl-D-glucosamine, an N-acetylglucosamine kinase inhibitor, for accurate assay of glucokinase in pancreatic islets and liver: I. Miwa, et al.; Enzyme Protein 48, 135 (1994), Abstract;
Inhibition of N-acetylglucosamine kinase and N-acetylmannosamine kinase by 3-O-methyl-N-acetyl-D-glucosamine in vitro: R. Zeitler, et al.; Eur. J. Biochem. 204, 1165 (1992), Abstract;

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