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United States 

PD 174,265

EGFR inhibitor
 
ALX-270-323-M001 1 mg 155.00 USD
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Potent, cell permeable, reversible, and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC50=450pM).

Product Specification

Alternative Name:4-[(3-Bromophenyl)amino]-6-propionylamidoquinazoline
 
Formula:C17H15BrN4O
 
MW:371.2
 
CAS:216163-53-0
 
Purity:≥97% (HPLC)
 
Appearance:Off white to yellow powder.
 
Solubility:Soluble in DMSO (200 mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light. Keep under inert gas.
 
270-323
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270-323

Product Literature References

Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor: D.W. Fry, et al.; PNAS 95, 12022 (1998), Abstract; Full Text

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