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PD 168,393

EGFR inhibitor
 
ALX-270-322-M001 1 mg 233.00 USD
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Potent, cell permeable, irreversible, and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC50=700pM). Antitumor agent in vivo.

Product Specification

Alternative Name:4-[(3-Bromophenyl)amino]-6-acrylamidoquinazoline
 
Formula:C17H13BrN4O
 
MW:369.2
 
CAS:194423-15-9
 
Purity:≥95% (HPLC)
 
Appearance:Yellow to orange solid.
 
Solubility:Soluble in DMSO (200 mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light. Keep under inert gas.
 
270-322
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270-322

Product Literature References

Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor: D.W. Fry, et al.; PNAS 95, 12022 (1998), Abstract; Full Text

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