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Compound 56

EGFR inhibitor
 
ALX-270-316-C500 500 µg 236.00 USD
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Potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) (IC50=6pM).

Product Specification

Alternative Name:4-[(3-Bromophenyl)amino]-6,7-diethoxyquinazoline
 
Formula:C18H18BrN3O2
 
MW:388.3
 
CAS:171745-13-4
 
Purity:≥97% (HPLC)
 
Appearance:White to off-white powder.
 
Solubility:Soluble in DMSO (200mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
270-316
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270-316

Product Literature References

Tyrosine kinase inhibitors. 8. An unusually steep structure-activity relationship for analogues of 4-(3-bromoanilino)-6,7-dimethoxyquinazoline (PD 153035), a potent inhibitor of the epidermal growth factor receptor: A.J. Bridges, et al.; J. Med. Chem. 39, 267 (1996), Abstract;

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