Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Indirubin-5-sulfonic acid . sodium salt

Inhibitor of CDK and GSK
 
ALX-270-296-M001 1 mg 82.00 USD
 
ALX-270-296-M005 5 mg 324.00 USD
Do you need bulk/larger quantities?
 
Inhibitor of cyclin-dependent kinases (CDKs), with selectivity for CDK1/cyclin B (IC50=55nM), CDK2/cyclin A (IC50=35nM), CDK2/cyclin E (IC50=150nM), CDK4/cyclin D1 (IC50=300nM), CDK5/p35 (IC50=65nM) and GSK-3β (IC50=280nM).

Product Specification

Alternative Name:E226, Indirubin-5-sulphonate . Na
 
Formula:C16H9N2O5S . Na
 
MW:341.3 . 23.0
 
Purity:≥95% (1H-NMR)
 
Identity:Determined by 1H-NMR.
 
Appearance:Black powder.
 
Solubility:Soluble in DMSO or water.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
270-296
Please mouse over
270-296

Product Literature References

Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors?: S. Leclerc, et al.; J. Biol. Chem. 276, 251 (2001), Abstract; Full Text
Inhibition of cyclin-dependent kinase 1 (CDK1) by indirubin derivatives in human tumour cells: D. Marko, et al.; Br. J. Cancer 84, 283 (2001), Abstract;
Inhibitor binding to active and inactive cdk2. the crystal structure of cdk2-cyclin a/indirubin-5-sulphonate: T.G. Davies, et al.; Structure (Camb) 9, 389 (2001), Abstract;
Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases: R. Hoessel, et al.; Nat. Cell. Biol. 1, 60 (1999), Abstract;

Related Products

Indirubin-3'-monoxime 

Inhibitor of CDK and GSK
160807-49-8, ≥98% | Print as PDF
 
BML-CC207-0001 1 mg 81.00 USD
 
BML-CC207-0005 5 mg 332.00 USD
Do you need bulk/larger quantities?
 

Indirubin 

Inhibitor of CDK and GSK
479-41-4, Synthetic., ≥98% (1H-NMR, HPLC) | Print as PDF
 
ALX-270-361-M001 1 mg 55.00 USD
 
ALX-270-361-M005 5 mg 240.00 USD
Do you need bulk/larger quantities?
 

5-Iodo-indirubin-3'-monoxime 

Inhibitor of GSK and CDK/cyclin
≥98% (1H-NMR) | Print as PDF
 
ALX-270-424-M001 1 mg 112.00 USD
Do you need bulk/larger quantities?
 

Me-7BIO 

≥98% | Print as PDF
 
ALX-430-157-M001 1 mg 106.00 USD
Do you need bulk/larger quantities?
 

6BIO 

Inibitor of phosphoinositide-dependent kinase 1 and GSK
667463-62-9, ≥98% (HPLC) | Print as PDF
 
ALX-430-156-M001 1 mg 60.00 USD
 
ALX-430-156-M005 5 mg 125.00 USD
Do you need bulk/larger quantities?
 

Related Literature

Brochures
Integrated solutions for screening Wnt regulators
Integrated solutions for screening Wnt regulators
Download as PDF

Brochures
Stem Cells
Stem Cells
Download as PDF

Catalogs
Diabetes Catalog
Diabetes Catalog
Download as PDF

Brochures
Essential Research Tools for Neurodegeneration & Neural Signaling
Essential Research Tools for Neurodegeneration & Neural Signaling
Download as PDF

Product Flyers
Cell Cycle - Mitosis, CDKS & Cell Cycle Signaling
Cell Cycle - Mitosis, CDKS & Cell Cycle Signaling
Download as PDF

Technical Posters
Disease-Associated Stress Signaling
Disease-Associated Stress Signaling
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,