Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Aminopurvalanol A

CDK/cyclin inhibitor
 
ALX-270-249-M001 1 mg 54.00 USD
 
ALX-270-249-M005 5 mg 162.00 USD
Do you need bulk/larger quantities?
 
Cell permeable, reversible and competitive inhibitor of CDK1/cyclin B (IC50=33nM), CDK2/cyclin A (IC50=33nM), CDK2/cyclin E (IC50=28nM) and CDK5/p35 (IC50=20nM).

Product Specification

Alternative Name:(2R)-2-((6-((3-Amino-5-chlorophenyl)amino)-9-(1-methylethyl)-9H-purin-2-yl)amino)-3-methyl-1-butanol, NG-97
 
Formula:C19H26N7OCl
 
MW:403.9
 
CAS:220792-57-4
 
Purity:≥97% (HPLC)
 
Identity:Determined by NMR.
 
Appearance:White to brownish solid.
 
Solubility:Soluble in DMSO or methanol.
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
Handling:Protect from light. Packaged under inert gas.
 
270-249
Please mouse over
270-249

Product Literature References

M-phase regulation of the recruitment of mRNAs onto polysomes using the CDK1/cyclin B inhibitor aminopurvalanol: M. Le Breton, et al.; BBRC 306, 880 (2003), Abstract;
A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: biochemical identification using Xenopus egg extracts: G.R. Rosania, et al.; PNAS 96, 4797 (1999), Abstract; Full Text
Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors: Y.T. Chang, et al.; Chem. Biol. 6, 361 (1999), Abstract;

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
CDK
Cyclin
By biological activity:
CDK Inhibitor
Cyclin Inhibitor
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Related Literature

Product Flyers
Cell Cycle - Mitosis, CDKS & Cell Cycle Signaling
Cell Cycle - Mitosis, CDKS & Cell Cycle Signaling
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,