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Purvalanol B

Cyclin-dependent kinase inhibitor.
 
ALX-270-247-M001 1 mg 53.00 USD
 
ALX-270-247-M005 5 mg 125.00 USD
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Purvalanol B inhibits cyclin-dependent kinases with IC50 values of 6, 6, 9, > 10,000, and 6 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively. Has also been shown to have anti-proliferative properties, mediated by p42/p44 MAPK.

Product Specification

Formula:C20H25ClN6O3
 
MW:432.9
 
CAS:212844-54-7
 
Purity Detail:≥98% (HPLC)
 
Identity:Determined by EM-MS and NMR.
 
Appearance:White powder.
 
Solubility:Soluble in DMSO (112mg/ml) or ethanol (4mg/ml).
 
Shipping:Ambient
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
ALX-270-247 structure
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ALX-270-247 structure

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