Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Purvalanol A

CDK/cyclin inhibitor
 
ALX-270-246-M001 1 mg 65.00 USD
 
ALX-270-246-M005 5 mg 277.00 USD
Do you need bulk/larger quantities?
 
Inhibitor of human CDK1 (IC50=4nM), CDK2/cyclin A (IC50=70nM), Cdc2/cyclin B, CDK2/cyclin E (IC50=35nM), CDK4/cyclin D1 (IC50=850nM) as well as CDK5/p35 (IC50=75nM). More membrane permeable than purvalanol B.

Product Specification

Alternative Name:6-[(3-Chloro)anilino]-2(1R)-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine
 
Formula:C19H25N6OCl
 
MW:388.9
 
CAS:212844-53-6
 
Purity:≥99% (NMR)
 
Appearance:Off-white to yellow powder.
 
Solubility:Soluble in DMSO, methanol or dichloromethane.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Keep under inert gas. Keep cool and dry.
 
270-246
Please mouse over
270-246

Product Literature References

Mitochondria localize to the cleavage furrow in mammalian cytokinesis: E.J. Lawrence, et al.; PLoS One 8, e72886 (2013), Abstract; Full Text
Roscovitine, olomoucine, purvalanol: inducers of apoptosis in maturing cerebellar granule neurons: E.A. Monaco, 3rd, et al.; Biochem. Pharmacol. 67, 1947 (2004), Abstract;
Up-regulation of cdc2 protein during paclitaxel-induced apoptosis: P. Chadebech, et al.; Int. J. Cancer 87, 779 (2000), Abstract;
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors: N.S. Gray, et al.; Science 281, 533 (1998), Abstract;

Related Literature

Brochures
Integrated solutions for screening Wnt regulators
Integrated solutions for screening Wnt regulators
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2019 Enzo Life Sciences, Inc.,