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bpV(HOpic)

PTP inhibitor, PTEN Inhibitor
 
ALX-270-206-M005 5 mg 75.00 USD
 
ALX-270-206-M025 25 mg 318.00 USD
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Protein phosphotyrosine phosphatase inhibitor.

Product Specification

Formula:K2[VO(O2)2C6H4NO3]
 
MW:347.2
 
Purity:≥90% (51V-NMR)
 
Appearance:Yellow crystalline solid.
 
Solubility:Soluble in DMSO or water. Note: This product is not stable in water. Starts decomposition immediately after solubilization. Rate of decomposition is slower in dry DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light and moisture.
 
ALX-270-206
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ALX-270-206

Product Literature References

Estrogen receptor beta signaling through phosphatase and tensin homolog/phosphoinositide 3-kinase/Akt/glycogen synthase kinase 3 down-regulates blood-brain barrier breast cancer resistance protein: A.M. Hartz, et al.; J. Pharmacol. Exp. Ther. 334, 467 (2010), Abstract; Full Text
Pharmacological inhibition of PTEN limits myocardial infarct size and improves left ventricular function postinfarction: K.T. Keyes, et al.; Am. J. Physiol. Heart Circ. Physiol. 298, H1198 (2010), Abstract; Full Text
Bisperoxovanadium compounds are potent PTEN inhibitors: A.C. Schmid, et al.; FEBS Lett. 566, 35 (2004), Abstract;
Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics: B.I. Posner, et al.; J. Biol. Chem. 269, 4596 (1994), Abstract; Full Text

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