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Benzamide

PARP-1 inhibitor
 
ALX-270-174-G005 5 g 30.00 USD
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Inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1). Neuroprotectant.

Product Specification

Formula:C7H7NO
 
MW:121.1
 
CAS:55-21-0
 
MI:14: 1060
 
RTECS:CU8700000
 
Purity:≥98.5% (GC)
 
Identity:Determined by IR.
 
Appearance:White to off-white solid.
 
Solubility:Soluble in 100% ethanol.
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
ALX-270-174
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ALX-270-174

Product Literature References

Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation: H. Kleine, et al.; Mol. Cell 32, 57 (2008), Abstract;
Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity: J. Zhang, et al.; Science 263, 687 (1994), Abstract;
Cytotoxicity of a new IMP dehydrogenase inhibitor, benzamide riboside, to human myelogenous leukemia K562 cells: H.N. Jayaram, et al.; BBRC 186, 1600 (1992), Abstract;

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The PARP Family & ADP Ribosylation
The PARP Family & ADP Ribosylation
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