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TRIM

nNOS inhibitor
 
ALX-270-170-M050 50 mg 33.00 USD
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Replaces Prod. #: BML-CN266

Potent neuronal nitric oxide synthase (nNOS; NOS I) inhibitor.

Product Specification

Alternative Name:1-(2-Trifluoromethylphenyl)imidazole
 
Formula:C10H7F3N2
 
MW:212.2
 
CAS:25371-96-4
 
Purity:≥98% (GC)
 
Appearance:White solid.
 
Solubility:Soluble in DMSO (30mg/ml) or dichloromethane (25%); slightly soluble in water (5mg/ml), 0.1 N HCl (6mg/ml) or 0.1 N NaOH (2mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
ALX-270-170
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ALX-270-170

Product Literature References

Antidepressant- and anxiolytic-like effects of selective neuronal NOS inhibitor 1-(2-trifluoromethylphenyl)-imidazole in mice: V. Volke, et al.; Behav. Brain Res. 140, 141 (2003), Abstract;
Cerebroprotective effect of the nitric oxide synthase inhibitors, 1-(2-trifluoromethylphenyl) imidazole and 7-nitro indazole, after transient focal cerebral ischemia in the rat: K.J. Escott, et al.; J. Cereb. Blood Flow Metab. 18, 281 (1998), Abstract;
Mechanism of the inhibition of neuronal nitric oxide synthase by 1-(2-trifluoromethylphenyl) imidazole (TRIM): R.L. Handy & P.K. Moore; Life Sci. 60, PL389 (1997), Abstract;
Inhibition of nitric oxide synthase by 1-(2-trifluoromethylphenyl) imidazole (TRIM) in vitro: antinociceptive and cardiovascular effects: R.L. Handy, et al.; Br. J. Pharmacol. 119, 423 (1996), Abstract;
The antinociceptive effect of 1-(2-trifluoromethylphenyl) imidazole (TRIM), a potent inhibitor of neuronal nitric oxide synthase in vitro, in the mouse: R.L. Handy, et al.; Br. J. Pharmacol. 116, 2349 (1995), Abstract;

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