Dephostatin

PTP inhibitor



ALX-270-169-M001	1 mg	122.00 USD

Competitive protein tyrosine phosphatase inhibitor. Protein S-nitrosating reagent.

Product Specification

Alternative Name:	2,5-Dihydroxy-N-methyl-N-nitrosoaniline

Identity:	Identity determined by NMR.

Formula:	C₇H₈N₂O₃

MW:	168.2

Purity:	≥90% (HPLC)

Appearance:	Red to brown solid.

CAS:	151606-30-3

RTECS:	CZ9021800

Source/Host:	Synthetic.

Solubility:	Soluble in DMSO, chloroform or methanol.

Long Term Storage:	-20°C

Handling:	Keep under inert gas. Protect from light and moisture.

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Product Literature References

Synthesis and Bioassay of a Protein Tyrosine Phosphatase Inhibitor, Dephostatin: L. Yu, et al.; Bioorg. Med. Chem. Lett. 5, 1003 (1995),

Synthesis and protein tyrosine phosphatase inhibitory activity of dephostatin analogs: T. Watanabe, et al.; J. Antibiot. 48, 1460 (1995), Abstract;

Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces. I. Taxonomy, isolation, and characterization: M. Imoto, et al.; J. Antibiot. 46, 1342 (1993), Abstract;

Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces. II. Structure determination: H. Kakeya, et al.; J. Antibiot. 46, 1716 (1993), Abstract;