Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

W-13 . hydrochloride

Calmodulin antagonist. PDE and MLCK inhibitor.
 
ALX-270-156-M005 5 mg 52.00 USD
Do you need bulk/larger quantities?
 
Antagonist of calmodulin, inhibiting activation of Ca2+/calmodulin-dependent phosphodiesterase (PDE I) and myosin light chain kinase.

Product Specification

Alternative Name:N-(4-Aminobutyl)-5-chloro-2-naphthalenesulfonamide . HCl
 
Formula:C14H17ClN2O2S . HCl
 
MW:312.8 . 36.5
 
Source:Synthetic.
 
CAS:88519-57-7
 
Purity:≥98% (TLC)
 
Identity:Determined by 1H-NMR and MS.
 
Appearance:White to beige solid.
 
Solubility:Soluble in water (warm) or methanol.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
ALX-270-156
Please mouse over
ALX-270-156

Product Literature References

Tamoxifen-resistant human breast cancer cell growth: inhibition by thioridazine, pimozide and the calmodulin antagonist, W-13: J.S. Stroble & V.A. Peterson; J. Pharm. Exp. Ther. 263, 186 (1992), Abstract;
Direct interaction of calmodulin antagonists with Ca2+/calmodulin- dependent cyclic nucleotide phosphodiesterase: H. Itoh & H. Hidaka; J. Biochem. 96, 1721 (1984), Abstract;
Calmodulin antagonists enhance calcium binding to calmodulin: M. Inagaki, et al.; Pharmacology 27, 125 (1983), Abstract;
Naphthalenesulfonamides as calmodulin antagonists: H. Hidaka & T. Tanaka; Meth. Enzymol. 102, 185 (1983), Abstract;
Activity-structure relationship of calmodulin antagonists, Naphthalenesulfonamide derivatives: H. Hidaka, et al.; Mol. Pharmacol. 20, 571 (1981), Abstract;
[Pharmacology of calmodulin: calmodulin antagonist (author's transl)]: H. Hidaka; Prot. Nucl. Acid Enz. 26, 977 (1981), Abstract;
Hydrophobic regions function in calmodulin-enzyme(s) interactions: T. Tanaka & H. Hidaka; J. Biol. Chem. 255, 11078 (1980), Abstract; Full Text

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,