W-12 . hydrochloride

Calmodulin antagonist. PDE and MLCK inhibitor.



ALX-270-155-M005	5 mg	26.00 USD

ALX-270-155-M025	25 mg	104.00 USD

Antagonist of calmodulin, inhibiting activation of Ca²⁺/calmodulin-dependent phosphodiesterase (PDE I) and myosin light chain kinase.

Product Specification

Alternative Name:	N-(4-Aminobutyl)-2-naphthalenesulfonamide . HCl

Formula:	C₁₄H₁₈N₂O₂S . HCl

MW:	278.4 . 36.5

Purity:	≥98%

Appearance:	White solid.

CAS:	89108-46-3

Solubility:	Soluble in 100% ethanol or water.

Long Term Storage:	-20°C

Handling:	Protect from light.

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Product Literature References

N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation: H. Hidaka, et al.; PNAS 78, 4354 (1981), Abstract;

[Pharmacology of calmodulin: calmodulin antagonist (author's transl)]: H. Hidaka; Prot. Nucl. Acid Enz. 26, 977 (1981), Abstract;

T. Tanaka and H. Hidaka; J. Biol. Chem. 255, 11078 (1980), Abstract; Full Text