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Naproxen

COX inhibitor. NSAID.
 
ALX-270-102-G005 5 g 43.00 USD
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Replaces Prod. #: BML-EI133

Cyclooxygenase (COX) inhibitor. Widely used non-steroidal anti-inflammatory drug.

Product Specification

Alternative Name:(S)-6-Methoxy-α-methyl-2-naphthalene acetic acid
 
Formula:C14H14O3
 
MW:230.3
 
CAS:22204-53-1
 
MI:14: 6417
 
Purity:≥98% (HPLC)
 
Appearance:White to off-white crystalline powder.
 
Solubility:Soluble in DMSO, dimethyl formamide and 100% ethanol.
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
ALX-270-102
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ALX-270-102

Product Literature References

Nonsteroidal anti-inflammatory drug naproxen destabilizes Abeta amyloid fibrils: a molecular dynamics investigation: T. Takeda, et al.; J. Phys. Chem. B. 114, 15394 (2010), Abstract; Full Text
Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma: M. Sastre, et al.; PNAS U.S.A. 103, 443 (2006), Abstract; Full Text
Constitutive cyclooxygenase (COX-1) and inducible cyclooxygenase (COX-2): rationale for selective inhibition and progress to date: D.E. Griswold & J.L. Adams; Med. Res. Rev. 16, 181 (1996), Abstract;
Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-inflammatory drugs: O. Laneuville, et al.; J. Pharmacol. Exp. Ther. 271, 927 (1994), Abstract;
Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus system: J. Barnett, et al.; Biochim. Biophys. Acta 1209, 130 (1994), Abstract;
Perspectives in nonsteroidal anti-inflammatory agents: T.Y. Shen; Angew. Chem. Int. Ed. 11, 460 (1972), Abstract;

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