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Bisindolylmaleimide III

PKC inhibitor
 
ALX-270-051-M001 1 mg 48.00 USD
 
ALX-270-051-M005 5 mg 172.00 USD
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Potent and selective inhibitor of protein kinase C (PKC).

Product Specification

Formula:C23H20N4O2
 
MW:384.4
 
Purity:≥98%
 
Identity:Determined by NMR.
 
Appearance:Red solid.
 
Solubility:Soluble in methanol or DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
ALX-270-051
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ALX-270-051

Product Literature References

Proteome-wide identification of cellular targets affected by bisindolylmaleimide-type protein kinase C inhibitors: D. Brehmer, et al.; Mol. Cell Proteomics 3, 490 (2004), Abstract; Full Text
Protein kinase C inhibitors; structure-activity relationships in K252c- related compounds: S. Fabre and M. Prudhomme; Bioorg. Med. Chem. 1, 193 (1993), Abstract;
Inhibitors of protein kinase C. 1. 2,3-Bisarylmaleimides: P.D. Davis, et al.; J. Med. Chem. 35, 177 (1992), Abstract;
The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C: D. Toullec, et al.; J. Biol. Chem. 266, 15771 (1991), Abstract; Full Text

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