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1,3-PB-ITU . dihydrobromide

iNOS inhibitor
 
ALX-270-026-M010 10 mg 15.00 USD
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Replaces Prod. #: BML-CN259

Potent and selective inhibitor of inducible nitric oxide synthase (iNOS; NOS II). Ki (iNOS)=47nM, Ki (eNOS)=9.0μM.

Product Specification

Alternative Name:S,S'-(1,3-Phenylene-bis(1,2-ethanediyl))bis-isothiourea . 2HBr, PBITU
 
Formula:C12H18N4S2 . 2HBr
 
MW:444.2
 
Purity:≥97%
 
Appearance:White to off-white powder.
 
Solubility:Soluble in water (25mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Hygroscopic.
 
ALX-270-026
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ALX-270-026

Product Literature References

Real-time electrochemical detection of extracellular nitric oxide in tobacco cells exposed to cryptogein, an elicitor of defence responses: A. Besson-Bard, et al.; J. Exp. Bot. 59, 3407 (2008), Abstract;
Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas: E.P. Garvey, et al.; J. Biol. Chem. 269, 26669 (1994), Abstract; Full Text

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