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L-NIL . dihydrochloride

NOS inhibitor
 
ALX-270-010-M010 10 mg 44.00 USD
 
ALX-270-010-M050 50 mg 168.00 USD
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Replaces Prod. #: BML-CN258

Selective inhibitor of inducible nitric oxide synthase (iNOS; NOS II). Shows anti-inflammatory activity.

Product Specification

Alternative Name:L-N6-(1-Iminoethyl)-lysine . 2HCl
 
Formula:C8H17N3O2 . 2HCl
 
MW:187.2 . 73.0
 
CAS:159190-45-1
 
Purity:≥97% (TLC)
 
Appearance:White to off-white solid.
 
Solubility:100mg/ml soluble in water or methanol.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Very hygroscopic. Keep under inert gas.
 
ALX-270-010
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ALX-270-010

Product Literature References

Ligation of CD40 in Human Müller Cells Induces P2X7 Receptor-Dependent Death of Retinal Endothelial Cells: JC. Portillo, et al.; Invest. Ophthalmol. Vis. Sci. 1, 6278 (2016), Abstract; Full Text
Adiponectin is a potential catabolic mediator in osteoarthritis cartilage: E.H. Kang, et al.; Arthritis Res. Ther. 12, R231 (2010), Abstract; Full Text
Dual inhibition of nitric oxide and prostaglandin production contributes to the antiinflammatory properties of nitric oxide synthase inhibitors: D. Salvemini, et al.; J. Clin. Invest. 96, 301 (1995), Abstract;
L-N6-(1-iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase: W.M. Moore, et al.; J. Med. Chem. 37, 3886 (1994), Abstract;

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