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Z-VRPR-FMK

MALT1 inhibitor
 
ALX-260-166-MC05 0.5 mg 284.00 USD
 
ALX-260-166-M001 1 mg 514.00 USD
 
The proteolytic activity of the paracaspase MALT1 is key to NF-κB and T cell activation. Z-VRPR-FMK is a selective MALT1 inhibitor of such proteolytic activity.

Product Specification

Alternative Name:Z-Val-Arg-Pro-DL-Arg-FMK, MALT1 inhibitor
 
Sequence:Z-Val-Arg-Pro-DL-Arg-fluoromethylketone
 
Formula:C31H49FN10O6
 
MW:676.8
 
Purity:≥90% (HPLC)
 
Appearance:White to slightly yellow powder.
 
Solubility:Soluble in water (1mg/ml).
 
Long Term Storage:-20°C
 
Handling:Hygroscopic. Avoid freeze/thaw cycles.
 

Product Literature References

Coregulation and modulation of NFκB-related genes in celiac disease: uncovered aspects of gut mucosal inflammation: N. Fernandez-Jimenez, et al.; Hum. Mol. Genet. 23, 1298 (2014), Application(s): Assay, Abstract; Full Text
Essential Role of the Linear Ubiquitin Chain Assembly Complex in Lymphoma Revealed by Rare Germline Polymorphisms: Y. Yang, et al.; Cancer Discov. 4, 480 (2014), Abstract; Full Text
Measurement of Endogenous MALT1 Activity: D. Nagel, et al.; Bio-protocol 3, 1 (2013), Full Text
Mechanism and specificity of the human paracaspase MALT1: J. Hachmann, et al.; Biochem. J. 443, 287 (2012), Application(s): Titration, Abstract; Full Text
The proteolytic activity of the paracaspase MALT1 is key in T cell activation: F. Rebeaud, et al.; Nat. Immunol. 9, 272 (2008), Abstract;

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