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Z-DEVD-FMK (Ready-to-Use)

Inhibitor of caspase-3 and -7
 
ALX-260-141-R100 100 µl 2mM 185.00 USD
 
ALX-260-141-R020 20 µl 10mM 185.00 USD
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Irreversible, cell permeable inhibitor of caspase-3 and -7.

Product Specification

Alternative Name:Caspase-3 inhibitor (fluoromethylketone), Caspase-7 inhibitor (fluoromethylketone)
 
Sequence:Z-Asp-Glu-Val-Asp-fluoromethylketone
 
MW:668.0
 
Formulation:Liquid. In DMSO.
 
Purity:≥98% (HPLC)
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Technical Info/Product Notes:We recommend a final concentration of 2µM for inhibiting caspase activity in Jurkat cell culture. The optimal doses may vary for different cells and culture conditions.
 
260-141
Figure: Apoptosis was induced in Jurkat cells with camptothecin in the presence of various concentrations (0-3μM) of Z-DEVD-FMK (Ready-to-Use) (Prod. No. ALX-260-141) as indicated. Caspase activity was analyzed using Caspase-3 Fluorometric Assay Kit (Prod. No. ALX-850-216).
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260-141

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