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Z-Phe-Tyr(tBu)-diazomethylketone

Cathepsin-L inhibitor
 
ALX-260-134-M001 1 mg 38.00 USD
 
ALX-260-134-M005 5 mg 112.00 USD
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Irreversible inhibitor of cathepsin L.

Product Specification

Alternative Name:Z-FY(tBu)-DMK
 
Formula:C31H34N4O5
 
MW:542.6
 
Purity:≥98%
 
Appearance:White to off-white powder.
 
Solubility:Soluble in ethyl acetate (10mg/ml) or DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 

Product Literature References

Identification of host factors involved in borna disease virus cell entry through a small interfering RNA functional genetic screen: R. Clemente, et al.; J. Virol. 84, 3562 (2010), Abstract; Full Text
Analysis of filovirus entry into vero e6 cells, using inhibitors of endocytosis, endosomal acidification, structural integrity, and cathepsin (B and L) activity: A. Sanchez; J. Infect. Dis. 196, S251 (2007), Abstract; Full Text
Loss of cathepsin L activity promotes claudin-1 overexpression and intestinal neoplasia: F. Boudreau, et al.; FASEB J. 21, 3853 (2007), Abstract; Full Text
The affinity-labelling of cathepsin S with peptidyl diazomethyl ketones. Comparison with the inhibition of cathepsin L and calpain: E. Shaw, et al.; FEBS Lett. 334, 340 (1993), Abstract;

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