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Substrate for caspase-1 and -4
ALX-260-108-M005 5 mg 115.00 USD
ALX-260-108-M010 10 mg 216.00 USD
Do you need bulk/larger quantities?
Fluorogenic substrate for caspase-1 and -4.

Product Specification

Alternative Name:Caspase-1 substrate (fluorogenic), Caspase-4 substrate (fluorogenic)
Sequence:Ac-Tyr-Val-Ala-Asp-AFC (AFC=7-Amino-4-trifluoromethylcoumarin)
Purity:≥97% (HPLC)
Appearance:White to off-white powder.
Solubility:Soluble in DMSO.
Long Term Storage:-20°C
Use/Stability:Solid product is stable for 1 year in desiccator when stored at room temperature. Stock solutions are stable for 6 – 8 months when stored at –20°C. Keep sealed after removing from the freezer until its temperature equilibrates with room temperature.
Handling:Keep cool and dry.
Technical Info/Product Notes:AFC has an excitation maximum of 400nm and an emission maximum of 505nm.

Product Literature References

Caspase-7 is activated during lovastatin-induced apoptosis of the prostate cancer cell line LNCaP: M. Marcelli, et al.; Cancer Res. 58, 76 (1998), Abstract;

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