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Z-VD(OMe)VAD(OMe)-FMK

Caspase-2 inhibitor
 
ALX-260-099-M001 1 mg 405.00 USD
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Irreversible, cell permeable inhibitor of caspase-2.

Product Specification

Alternative Name:Caspase-2 inhibitor (fluoromethylketone)
 
Sequence:Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-fluoromethylketone
 
Formula:C32H46FN5O11
 
MW:695.7
 
Purity:≥99% (TLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Store stock solutions in aliquots at -20°C.
 
Handling:Keep cool and dry.
 

Product Literature References

Distinct pathways for stimulation of cytochrome c release by etoposide: J.D. Robertson, et al.; J. Biol. Chem. 275, 32438 (2000), Abstract; Full Text
Function of caspases in regulating apoptosis caused by erythropoietin deprivation in erythroid progenitors: P.A. Gregoli & M.C. Bondurant; J. Cell Physiol. 178, 133 (1999), Abstract;
Substrate specificities of caspase family proteases: R.V. Talanian, et al.; J. Biol. Chem. 272, 9677 (1997), Abstract; Full Text

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