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Antipain

Papain inhibitor
 
ALX-260-093-M005 5 mg 41.00 USD
 
ALX-260-093-M025 25 mg 156.00 USD
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Inhibits papain and trypsin and to a small extent plasmin. Antipain is more specific for papain and trypsin than is leupeptin (Prod. No. ALX-260-009). The inhibitory potency of antipain is 100-fold higher than that of elastatinal. Acts by forming a hemiacetal adduct between its aldehyde group and the active serine of the proteinase.

Product Specification

Alternative Name:[(S)-1-Carboxy-2-phenylethyl]-carbamoyl-Arg-Val-arginal . 2HCl
 
Sequence:[(S)-1-Carboxy-2-phenylethyl]-carbamoyl-Arg-Val-arginal
 
Formula:C27H44N10O6 . 2HCl
 
MW:604.7 . 72.9
 
Source:Synthetic.
 
CAS:37682-72-7
 
Purity:≥97% (HPLC)
 
Appearance:White to off-white powder.
 
Activity:Inhibitory Activity ≥30 U/mg (Trypsin, L-BAPA)
 
Solubility:Soluble in water, methanol, 100 % ethanol or acetonitrile.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
ALX-260-093 structure
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ALX-260-093 structure

Product Literature References

Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies: I. Albrecht, et al.; J. Clin. Invest. 125, 4612 (2015), Application(s): Skeletal muscle cell culture, Abstract; Full Text
Structures and activities of protease inhibitors of microbial origin: H. Umezawa; Meth. Enzymol. 45, 678 (1976), Abstract;
Antipain, a new protease inhibitor isolated from actinomycetes: H. Suda, et al.; J. Antibiot. 25, 263 (1972), Abstract;

Related Products

Leupeptin (synthetic) 

Cathepsin B inhibitor
103476-89-7, Synthetic., ≥97% (HPLC) | Print as PDF
 
ALX-260-009-M005 5 mg 41.00 USD
 
ALX-260-009-M025 25 mg 131.00 USD
 
ALX-260-009-M100 100 mg 460.00 USD
Do you need bulk/larger quantities?
 

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