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Ac-DMQD-AMC

Caspase-3 substrate
 
ALX-260-078-M001 1 mg 53.00 USD
 
ALX-260-078-M005 5 mg 187.00 USD
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Fluorogenic substrate for caspase-3.

Product Specification

Alternative Name:Caspase-3 substrate (fluorogenic)
 
Sequence:Ac-Asp-Met-Gln-Asp-AMC (AMC=7-Amino-4-methylcoumarin)
 
Formula:C30H38N6O12S
 
MW:706.7
 
Peptide Content:75-95%.
 
Purity:≥98% (HPLC)
 
Appearance:White powder.
 
Solubility:Soluble in DMSO. Dilute with distilled water or buffer. Also soluble in phosphate buffer, pH 7.5
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Keep cool and dry.
 
Technical Info/Product Notes:AMC has an excitation maximum of 340-360nm and an emission maximum of 440-460nm.
 

Product Literature References

Interaction of polyunsaturated fatty acids and sodium butyrate during apoptosis in HT-29 human colon adenocarcinoma cells: J. Hofmanova; Eur. J. Nutrition 44, 40 (2005), Abstract;
Bid truncation, bid/bax targeting to the mitochondria, and caspase activation associated with neutrophil apoptosis are inhibited by granulocyte colony-stimulating factor: N.A. Maianski, et al.; J. Immunol. 172, 7024 (2004), Abstract;
The effects of TNF-alpha and inhibitors of arachidonic acid metabolism on human colon HT-29 cells depend on differentiation status: M. Kovarikova, et al.; Differentiation 72, 23 (2004), Abstract;

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