Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Suc-Leu-Tyr-AMC

Protease substrate
 
ALX-260-054-M005 5 mg 35.00 USD
Do you need bulk/larger quantities?
 
Replaces Prod. #: BML-P130

Substrate for porcine calpain I and II. Also cleaved by papain and E. coli protease Ti. Ex.: 340-360nm, Em.: 440-460nm. This substrate is useful for inhibitor screening and kinetic analysis.

Product Specification

Alternative Name:Suc-LY-AMC
 
Sequence:Suc-Leu-Tyr-AMC (AMC=7-Amino-4-methylcoumarin)
 
Formula:C29H33N3O8
 
MW:551.6
 
CAS:94367-20-1
 
Purity:≥95%
 
Appearance:White to off-white powder.
 
Solubility:Soluble in 80% acetic acid, DMSO or methanol.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 

Product Literature References

Synthesis of a reported calpain inhibitor isolated from Streptomyces griseus: I.O. Donkor & M.L. Sanders; Bioorg. Med. Chem. Lett. 11, 2647 (2001), Abstract;
Na+, K+-specific inhibition of protein and peptide hydrolyses by proteasomes from human hepatoma tissues: J.H. Seol, et al.; FEBS Lett. 247, 197 (1989), Abstract;
Protease Ti from Escherichia coli requires ATP hydrolysis for protein breakdown but not for hydrolysis of small peptides: K.M. Woo, et al.; J. Biol. Chem. 264, 2088 (1989), Abstract; Full Text
Comparative specificity and kinetic studies on porcine calpain I and calpain II with naturally occurring peptides and synthetic fluorogenic substrates: T. Sasaki, et al.; J. Biol. Chem. 259, 12489 (1984), Abstract;

Recommend this page

 
Keep in touch

©2017 Enzo Life Sciences, Inc.,